Helen Blaine is the secretary of Dorian Creech at the Santa Barbara branch of Central Coast Pharmaceuticals and therefore one of Gus's colleagues. She is treated very harshly by her boss, and one morning she retaliates by squirting some eye drops in his coffee. When she finds him dead later that day, Helen is worried that her little act of revenge might have just made her a murderer. She therefore calls in sick the next day and doesn't attend the in-office memorial service. Knowing she would have a motive to kill Creech, Shawn and Gus find this very suspicious and go to question her during her jogging session. She tells them her story and is relieved to find out that Creech died from stab wounds rather than her eye drops (although they did make him vomit). Shawn and Gus believe her, and Helen is subsequently proven to be in great cardiovascular health as she speeds away in delight from the panting duo.